Junhyuk Chang
Junhyuk Chang
장준혁
Pharm.D.
Integrated Ph.D. Candidate
Department of Biomedical Sciences
Ajou University School of Medicine
Mar. 2022 –
wkd9504@ajou.ac.kr
wnsgur9504@gmail.com
Ajou University School of Medicine, Suwon, Korea
Research Interests
Causal Machine Learning Pharmacoepidemiology OMOP-CDM / Real-World Data Individualized Treatment Effects Medical Informatics Natural Language Processing

About


I am an Integrated Ph.D. candidate in Biomedical Sciences at Ajou University, working at the intersection of causal inference, pharmacoepidemiology, and medical informatics. My research aims to extract individualized treatment effect estimates from large-scale real-world clinical databases (OMOP-CDM) using causal machine learning frameworks.

With a background as a licensed pharmacist (Pharm.D., Ajou University 2022), I bridge clinical domain knowledge and data science — enabling rigorous interpretation of complex causal analyses and effective collaboration with clinicians and data scientists alike.

My ongoing work extends toward Multi-Agent Causal AI: building LLM-integrated pipelines that automate cohort construction, treatment effect estimation, counterfactual simulation, and clinical report generation — with the goal of advancing precision medicine at scale.

[ Education ]
  • Integrated Ph.D. course, Department of Biomedical Sciences, Ajou University  ·  Mar. 2022 –
  • College of Pharmacy, Ajou University  ·  2018 – 2022
[ Licenses & Certifications ]
  • Doctor of Pharmacy (Pharm.D.)  ·  Ministry of Health and Welfare, Mar. 2022
  • Advanced Data Analytics Semi-Professional (ADsP)  ·  Korea Data Agency, Jun. 2021

Publications


[ SCI(E)-Indexed Peer-Reviewed Articles ]

2025
Clustering of patients with severe asthma based on long-term percentage of forced expiratory volume in 1 second (FEV1) changes: Real-world evidence 1st Author
Lee Y, Chang J, Kim C, et al.
Annals of Allergy, Asthma & Immunology, 2025
Performance of Open-Source Large Language Models in Psychiatry: Usability Study Through Comparative Analysis of Non-English Records and English Translations 1st Author
Kim MG, Hwang G, Chang J, Chang S, Roh HW, Park RW
Journal of Medical Internet Research, 2025;27:e69857
Renal and Safety Outcomes of SGLT2 Inhibitors with Type 2 Diabetes: A Nationwide Observational Cohort Study 1st Author
Chang J, Kim C, Choi H, Park RW, Lee S
Journal of Clinical Medicine, 2025;14(10):3349
Rosuvastatin Versus Atorvastatin for Cardiovascular Disease Risk in Patients with Type 2 Diabetes: A Korean Cohort Study
Kim C, Chang J, Gan S, et al.
Pharmaceuticals, 2025;18(12):1860
Impact of Regulatory Post-Market Safety Advisories on Prescribing Practices: An Interrupted Time Series Analysis
Kim S, Kim S, Kim C, Chang J, et al.
Clinical Pharmacology & Therapeutics, 2025;117(6):1754–1762
2024
Adverse impacts of corticosteroid treatment on osteoporosis/osteopenia in adult asthmatics: A retrospective ICARUS cohort study 1st Author
Chang J, Jeon HS, Kim C, et al.
Journal of Allergy and Clinical Immunology: In Practice, 2024;13(2):310–319
Enhancing readmission prediction models by integrating insights from home healthcare notes: Retrospective cohort study
Gan S, Kim C, Chang J, et al.
International Journal of Nursing Studies, 2024;158:104850
2023
Impact of Trimetazidine on the Incident Heart Failure After Coronary Artery Revascularization 1st Author
Park S, Chang J, Hong SP, et al.
Journal of Cardiovascular Pharmacology, 2023;82(4):318–326

[ Other Peer-Reviewed Journals ]

2023
Association of Rhabdomyolysis in the Elderly Patients with Combination Therapy of Cytochrome 3A4 Substrates and Inhibitors Based on the Korean Claims Data 1st Author
Chang J, Choo E, Park RW, Lee S
Pharmacoepidemiology and Risk Management, 2023;15(1):81–93

Conference


2026
[ Upcoming ]
KoPERM, AI Causal Inference Session  ·  May 2026
  • Chang J. Data-Driven Causal Inference: Treatment Effect Analysis and Clinical Research Cases Using Causal Machine Learning. Invited Talk
2025
[ Oral ]
Asian Conference on Pharmacoepidemiology  ·  Nov. 2025
  • Chang J, et al. Individualized treatment effect estimation in bipolar disorder: A causal machine learning approach.
KoPERM  ·  Oct. 2025
  • Chang J, et al. Causal Learning with Large-Scale Propensity Scores to Predict Treatment Outcomes: A Study of Bipolar Disorder in Adults with ADHD.
[ Poster ]
Global OHDSI Symposium  ·  Oct. 2025
  • Chang J, et al. Causal Learning with Large-Scale Propensity Scores to Predict Treatment Outcomes: A Study of Bipolar Disorder in Adults with ADHD.
2024
[ Poster ]
Global OHDSI Symposium  ·  Oct. 2024
  • Chang J, et al. Causal Learning with Large-Scale Propensity Scores to Predict Treatment Outcomes: A Study of Arrhythmia in Adolescents with ADHD.
ISPE Annual Meeting (International Society for Pharmacoepidemiology)  ·  Aug. 2024
  • Chang J, et al. Effectiveness and Safety of SGLT2 Inhibitor Treatment on Renal Outcomes in Patients with Type 2 Diabetes: A Nationwide Observational Cohort Study in South Korea.
2023
[ Oral / Symposium ]
KOSMI Fall Conference  ·  Nov. 2023
  • Chang J, et al. Application of GPT for Prediction of Psychiatric Admission. Symposium
  • Chang J, et al. A de-identification model for Korean clinical notes using deep learning models. Oral
[ Poster ]
MEDINFO  ·  Jul. 2023
  • Chang J, et al. A de-identification model for Korean clinical notes using deep learning models.

Invited Talks


2026
KoPERM, AI Causal Inference Session  ·  May 2026 Upcoming
  • Data-Driven Causal Inference: Treatment Effect Analysis and Clinical Research Cases Using Causal Machine Learning
2025
Ulsan University Hospital, CDM Symposium  ·  Apr. 2025
  • CDM Symposium — Invited Lecture
2024
HIRA CDM Seminar, Health Insurance Review and Assessment Service  ·  Nov. 2024
  • Real-World Research Cases Utilizing HIRA Common Data Model — Invited Lecture

Projects


[ Government-Funded Research Projects ]

2025 – 2029 보건의료기술연구개발사업: 응급AI·CDSS 개발·실증·배포 플랫폼 기반 응급의료의 디지털 혁신
응급실 증후군 시계열 모델 개발 총괄 및 1단계 PM
2025 – 2027 국내 RWE 활용 의약품 안전성·유효성 평가 가이드라인(안) 개발 연구
EMR 활용 RWD/RWE 가이드라인 작성 및 사례연구 지원
2024 – 2026 의료기기실사용정보활용 CDM 구축 및 운영 과제
과제 PM 및 24년도 다기관 도커환경 분석 수행, 25–26년도 과제 분석 총괄
2022 – 2024 감염병환자정보시스템개발사업: 감염병 환자정보 관리 통합 시스템 개발
자연어 note 비식별화 모델 개발 및 3차년도 PM

[ Industry Collaboration ]

Conducted collaborative RWE research projects with leading pharmaceutical companies.
AstraZeneca
Sanofi
Handok

Skills


Causal Inference
Causal Forest TMLE IPTW Doubly-Robust Estimation Propensity Score Matching
Programming
Python R SQL Docker
Data / AI
OMOP-CDM ATLAS / OHDSI NLP / LLM RAG Multi-Agent Systems
Domain
Pharmacoepidemiology Medical Informatics CDM Mapping RWE Research Clinical Data Analysis